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Case Report

Online Publishing Date:
10 / 05 / 2023

 


Systemic Lupus Erythematosus (SLE): An Often-overlooked Cause of Cytopenias

Henry J. Ekpenyong, Hakeem B. Olaosebikan, Onosenigbuan S. Onwualu, Idowu E. Alabi, Hassana H. Aliyu.


Abstract
Background: Haematological manifestations are common in SLE, but cytopenias are rarely the only abnormality at diagnosis.
Case Summary: We report the case of a 40-year-old woman who was admitted for recurrent anaemia with a 2-month history of constitutional symptoms and no other complaints. Her Full Blood Count (FBC) showed bi-cytopenia, a Haemoglobin level of 4g/dl and a platelet level of 77x10³/μl. An Autoimmune serology revealed a positive Antinuclear antibody (ANA) test at 1:2560 and positive SLE antibodies. The diagnosis of SLE was established using the European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) 2019 classification criteria. She was commenced on steroids and Disease Modifying Anti-Rheumatic Drugs (DMARD), and there was a sustained increase in her Haemoglobin and platelet count. She subsequently required no further blood transfusions.
Conclusion: SLE can present in a myriad of ways. It is, however, essential to note that haematological features may be the sole manifestation at the time of diagnosis. Early recognition and commencement of appropriate treatment often improve prognosis.

Key words: SLE, Cytopenias, Haematological, Anaemia


 
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How to Cite this Article
Pubmed Style

Ekpenyong HJ, Olaosebikan HB, Onwualu OS, Alabi IE, Aliyu HH. Systemic Lupus Erythematosus (SLE): An Often-overlooked Cause of Cytopenias. crjmed. 2023; 2(1): 4-8. doi:10.5455/CRJMED.146005

Web Style

Ekpenyong HJ, Olaosebikan HB, Onwualu OS, Alabi IE, Aliyu HH. Systemic Lupus Erythematosus (SLE): An Often-overlooked Cause of Cytopenias. https://www.crjmed.com/?mno=146005 [Access: May 12, 2024]. doi:10.5455/CRJMED.146005

AMA (American Medical Association) Style

Ekpenyong HJ, Olaosebikan HB, Onwualu OS, Alabi IE, Aliyu HH. Systemic Lupus Erythematosus (SLE): An Often-overlooked Cause of Cytopenias. crjmed. 2023; 2(1): 4-8. doi:10.5455/CRJMED.146005


Vancouver/ICMJE Style

Ekpenyong HJ, Olaosebikan HB, Onwualu OS, Alabi IE, Aliyu HH. Systemic Lupus Erythematosus (SLE): An Often-overlooked Cause of Cytopenias. crjmed. (2023), [cited May 12, 2024]; 2(1): 4-8. doi:10.5455/CRJMED.146005


Harvard Style

Ekpenyong, H. J., Olaosebikan, . H. B., Onwualu, . O. S., Alabi, . I. E. & Aliyu, . H. H. (2023) Systemic Lupus Erythematosus (SLE): An Often-overlooked Cause of Cytopenias. crjmed, 2 (1), 4-8. doi:10.5455/CRJMED.146005


Turabian Style

Ekpenyong, Henry J., Hakeem B. Olaosebikan, Onosenigbuan S. Onwualu, Idowu E. Alabi, and Hassana H. Aliyu. 2023. Systemic Lupus Erythematosus (SLE): An Often-overlooked Cause of Cytopenias. Cross River Journal of Medicine, 2 (1), 4-8. doi:10.5455/CRJMED.146005


Chicago Style

Ekpenyong, Henry J., Hakeem B. Olaosebikan, Onosenigbuan S. Onwualu, Idowu E. Alabi, and Hassana H. Aliyu. "Systemic Lupus Erythematosus (SLE): An Often-overlooked Cause of Cytopenias." Cross River Journal of Medicine 2 (2023), 4-8. doi:10.5455/CRJMED.146005


MLA (The Modern Language Association) Style

Ekpenyong, Henry J., Hakeem B. Olaosebikan, Onosenigbuan S. Onwualu, Idowu E. Alabi, and Hassana H. Aliyu. "Systemic Lupus Erythematosus (SLE): An Often-overlooked Cause of Cytopenias." Cross River Journal of Medicine 2.1 (2023), 4-8. Print. doi:10.5455/CRJMED.146005


APA (American Psychological Association) Style

Ekpenyong, H. J., Olaosebikan, . H. B., Onwualu, . O. S., Alabi, . I. E. & Aliyu, . H. H. (2023) Systemic Lupus Erythematosus (SLE): An Often-overlooked Cause of Cytopenias. Cross River Journal of Medicine, 2 (1), 4-8. doi:10.5455/CRJMED.146005


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